spinal cord injuries

Tadpole Nerve Regeneration Could Give a Clue for Treating Spinal Cord Injuries

February 28, 2022 | Benjamin S. Persons, IV

Researchers at Nagoya University recently identified a gene that plays a vital role in regenerating the neurons of tadpoles. They conducted experiments on African clawed frog tadpoles and discovered that the gene helps aid recovery for spinal cord injuries. Medical experts hope that this discovery will help them develop better medical treatment options for spinal cord injuries. As of right now, there are minimal treatment options outside of physical and occupational therapy for patients with spinal cord injuries.

Injecting the Gene Led to a Partial Recovery

The researchers injected mice with the gene. Specifically, they injected the gene into the mice’s spinal cords and found that the mice who received the injection had partial recovery of their lost motor functions. First, the researchers analyzed the gene expression profiles for tadpoles regarding spinal cord injuries. They discovered that a gene called Neurod4 was expressed during the nerve regeneration process in tadpoles. They hypothesize that using this gene in mice could help aid neural tissue regeneration after an injury.

Exploring Spinal Cord Injuries

August 27, 2021 | Benjamin S. Persons, IV

Spinal cord injuries can have devastating physical and mental effects. These types of injuries often require extensive treatment which could last for months or even several years. The following article will prove an in-depth analysis of spinal cord injuries.

What are Some Types of Spinal Cord Injuries?

The severity of a spinal cord injury is classified as either “complete” or “incomplete.”

Spinal Cord Injuries Often Severe and Costly

December 18, 2020 | Benjamin S. Persons, IV

Spinal cord injuries have many causes, but at its most basic, a spinal cord injury is an injury to the spinal cord as a result of trauma leading to some level of loss of function of the spinal cord. This usually translates into a loss of body functions, as the nerves that control the body all pass through the spinal cord. Such loss of function can include anything from loss of feeling in the extremities – anything from temporary numbness in a finger or two all the way to permanent loss of feeling in an arm or a leg – all the way to paralysis, where you lose the ability to move parts of your body. Further, nerves do not heal, particularly in the case of a break in the spinal cord, meaning that spinal cord injuries are considerably more likely than other types of injuries to lead to long-term or permanent disability. These kinds of injuries can be both debilitating and expensive. The legal and health care legal costs related to spinal cord injuries are more than $29 billion each year and rising.

Traffic Accidents are the Main Cause of Spinal Cord Injuries

Traffic accidents, including passenger vehicle and motorcycle accidents, are the leading cause of spinal cord injuries each year in the United States. Traffic accidents account for almost half of all spinal cord injuries in the U.S. annually. This unwelcome distinction falls disproportionately upon motorcycle riders, who are easily the least well-protected users of the nation’s roads and highways. Even with a helmet on, a motorcycle rider is more exposed than anyone in the smallest, lightest passenger vehicle. In a collision with another vehicle, or even a single-vehicle accident, the motorcyclist almost always incurs worse injuries than the occupant of a passenger vehicle. Motorcycle riders have no steel cocoon surrounding them, nor anything to keep them from flying from their vehicles – rather, they are practically certain of being thrown from their bikes in an accident. This leaves motorcycle riders especially vulnerable to spinal cord injuries. In addition to colliding with another vehicle, they all too frequently are thrown from their bike and hit some other object, whether it be a tree, sign, telephone pole, another vehicle, or even “just” the pavement.